PRIVERMECTIN POUR-ON FOR CATTLE- ivermectin solution
FIRST PRIORITY INCORPORATED
Consult your veterinarian for assistance in the diagnosis, treatment and control of parasitism.
Privermectin® Pour-On for Cattle (ivermectin) delivers internal and external parasite control in one convenient low-volume application. Ivermectin is a potent anti-parasitic agent whose chemical structure is different from those of other antiparasitic agents.
Ivermectin is a member of the macrocylic lactone class of endectocides which have a unique mode of action. Compounds of the class bind selectively and with high affinity to glutamategated chloride ion channels which occur in invertebrate nerve and muscle cells.
This leads to an increase in the permeability of the cell membrane to chloride ions with hyperpolarization of the nerve or muscle cell, resulting in paralysis and death of the parasite. Compounds of this class may also interact with other ligandgated chloride channels, such as those gated by the neurotransmitter gamma-aminobutyric acid (GABA).
The margin of safety for compounds of this class is attributable to the fact that mammals do not have glutamategated chloride channels, the macrocyclic lactones have a low affinity for other mammalian ligand-gated chloride channels and they do not readily cross the blood-brain barrier.
Privermectin® Pour-On for Cattle (ivermectin) applied at the recommended dose level of 500 mcg/kg is indicated for the effective control of these parasites.
Ostertagia ostertagi (adults and L4)
(including inhibited stage)
Haemonchus placei (adults and L4)
Trichostrongylus axei (adults and L4)
T. colubriformis (adults and L4)
Cooperia oncophora (adults and L4)
Cooperia punctata (adults and L4)
Cooperia surnabada (adults and L4)
Strongyloides papillosus (adults)
Oesophagostomum radiatum (adults and L4)
Dictyocaulus viviparus (adults and L4)
Cattle Grubs (parasitic stages)
Sarcoptes scabiei var. Bovis
Privermectin® Pour-On for Cattle (ivermectin) has been proved to effectively control infections and to protect cattle from re-infection with: Oesophagostomum radiatum and Dictyocaulus viviparous for 28 days after treatment; Cooperia punctata and Trichostrongylus axei for 21 days after treatment; Ostertagia ostertagi, Haemonchus placei, Cooperia oncophora and Cooperia surnabada for 14 days after treatment; Damalinia bovis for 56 days after treatment.
Treatment for Cattle for Horn Flies
Privermectin® Pour-On for Cattle (ivermectin) controls horn flies (Haematobia irritans) for up to 28 days after dosing. For best results Privermectin® Pour-On for Cattle (ivermectin) should be part of a parasite control program for both internal and external parasites based on the epidemiology of these parasites. Consult your veterinarian or an entomologist for the most effective timing of applications.
The dose rate is 1 mL for each 22 lb of body weight. The formulation should be applied along the topline in a narrow strip extending from the withers to the tailhead.
Measuring Cup (250 mL, and 1 L bottles).
The enclosed measuring cup is graduated in 5 mL increments. Each 5 mL will treat 110 lbs body weight. When body weight is between markings, use the next higher increment.
(2.5 L, 5 L and 5 gallon bottles)
Because of the solvents used in Privermectin® Pour-On for Cattle (ivermectin), the applicator gun from Genesis Instruments (EZ Doser™ or Power Doser™) or equivalent is recommended. Other applicators may exhibit compatibility problems, resulting in locking, incorrect dosage or leakage.
EZ Doser™ Operation:
Power Doser™ Operation:
Follow the applicator gun manufacturer’s directions for priming the gun, adjusting the dose, and care of the applicator gun following use.
*Additional applicator guns can be purchased from Genesis Instruments, Elmwood, Wisconsin.
Studies conducted in the U.S.A. have demonstrated the safety margin for Ivermectin. Based on plasma levels, the topically applied formulation is expected to be at least as well tolerated by breeding animals as is the subcutaneous formulation which had no effect on breeding performance.
NOT FOR USE IN HUMANS.
Keep this and all drugs out of the reach of children.
The Material Safety Data Sheet (MSDS) contains more detailed occupational safety information.
To report adverse effects, obtain an MSDS or for assistance, contact Customer Service at 1-800-650-4899.
KEEP AWAY FROM HEAT, SPARKS, OPEN FLAME, AND OTHER SOURCES OF IGNITION.
This product should not be applied to self or others because it may be irritating to human skin and eyes and absorbed through the skin. To minimize accidental skin contact, the user should wear a long-sleeved shirt and rubber gloves. If accidental skin contact occurs, wash immediately with soap and water. If accidental eye exposure occurs, flush eyes immediately with water and seek medical attention.
Cattle must not be treated within 48 days of slaughter for human consumption. Because a withdrawal time in milk has not been established, do not use in female dairy cattle of breeding age. A withdrawal period has not been established for this product in pre-ruminating calves. Do not use in calves to be processed for veal.
Privermectin® Pour-On for Cattle (ivermectin) effectively controls all stages of cattle grubs. However, proper timing of treatment is important. For the most effective results, cattle should be treated as soon as possible after the end of the heel fly (warble fly) season. While this is not peculiar to ivermectin, destruction of Hypoderma larvae (cattle grubs) at the period when these grubs are in vital areas may cause undesirable host-parasite reactions. Killing Hypoderma lineatum when it is in the esophageal tissues may cause bloat; killing H. bovis when it is in the vertebral canal may cause staggering or paralysis. Cattle should be treated either before or after these stages of grub development.
Cattle treated with Privermectin® Pour-On for Cattle (ivermectin) at the end of the fly season may be re-treated with Privermectin® Pour-On for Cattle (ivermectin) during the winter without danger of grub-related reactions. For further information and advice on a planned parasite control program, consult your veterinarian.
Studies indicate that when ivermectin comes in contact with the soil, it readily and tightly binds to the soil and becomes inactive over time. Free ivermectin may adversely affect fish and certain aquatic organisms. Do not permit cattle to enter lakes, streams or ponds for at least six hours after treatment. Do not contaminate water by direct application or by the improper disposal of drug containers. Dispose of containers in an approved landfill or by incineration.
As with other avermectins, ivermectin is excreted in the dung of treated animals and can inhibit the reproduction and growth of pest and beneficial insects that use dung as a source of food and for reproduction. The magnitude and duration of such effects are species and life-cycle specific. When used according to label directions, the product is not expected to have an adverse impact on populations of dung-dependent insects.
Privermectin®Pour-On for Cattle(ivermectin)
FIRST PRIORITY, INC., 1590 Todd Farm Drive, Elgin, IL U.S.A.
Restricted Drug (California) - Use Only as Directed
Privermectin® Pour-On for Cattle is available in a 250 mL (8.5 fl oz), a 1 L (33.8 fl oz) and a 1 Gallon (3.785 L) bottle for use with the measuring cup provided, a 2.5 L (84.5 fl oz) container, 5 L (169.0 fl oz) container, and a 5 Gallon (639.0 fl oz) container for use with the appropriate automatic dosing applicator.
POUR-ON FOR CATTLE
ivermectin cattle pour-on solution
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