NEO-TERRAMYCIN 100/100- neomycin-oxytetracycline powder 
Phibro Animal Health

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Neo-Terramycin® 100/100
(neomycin-oxytetracycline)
TYPE A MEDICATED ARTICLE

(Antibiotic)

Active Drug Ingredients:

Oxytetracycline (from oxytetracycline dihydrate)

equivalent to oxytetracycline hydrochloride . . . . . . . . . . . . . . . . . . . . . . . . . . 100 g/lb

Neomycin Sulfate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 100 g/lb

CAUTION:

CAUTION: Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

CAUTION: For use in manufacturing medicated animal feeds only.

CAUTION: Certain components of animal feeds, including medicated premixes, possess properties that may be a potential health hazard or a source of personal discomfort to certain individuals who are exposed to them. Human exposure should, therefore, be minimized by observing the general industry standards for occupational health and safety.

Precautions such as the following should be considered: dust masks or respirators and protective clothing should be worn; dust-arresting equipment and adequate ventilation should be utilized; personal hygiene should be observed; wash before eating or leaving a work site; be alert for signs of allergic reactions—seek prompt medical treatment if such reactions are suspected.

STORE IN A DRY, COOL PLACE

STORE AT OR BELOW 25°C (77°F), EXCURSIONS PERMITTED UP TO 40°C (104°F)

FOR USE IN DRY FEEDS ONLY. NOT FOR USE IN LIQUID FEED SUPPLEMENTS.

MIXING AND USE DIRECTIONS

Thoroughly mix the amount of this Type A Medicated Article according to the directions below withat least an equal amount by weight of feed ingredients prior to blending into a complete feed.

Indications for Use

Oxytetracycline and Neomycin Amount

lb. of Neo-Terramycin 100/100 per ton

CHICKENS

Control of infectious synovitis caused by Mycoplasma synoviae; control of fowl cholera caused by Pasteurella multocida susceptible to oxytetracycline

100-200 g/ton

Feed continuously for 7-14 days

1-2

Control of chronic respiratory disease (CRD) and air sac infection caused by Mycoplasma gallisepticum and E. coli susceptible to oxytetracycline

400 g/ton

Feed continuously for 7-14 days

4

Reduction of mortality due to air sacculitis (air sac infection) caused by E. coli susceptible to oxytetracycline

500 g/ton

Feed continuously for 5 days

5

WARNING: At 500 g/ton level, withdraw 24 hours before slaughter. Low calcium feeds at 500 g/ton, withdraw 3 days before slaughter. Zero-day withdrawal period for lower use levels. In low calcium feeds withdraw 3 days before slaughter. Do not administer to chickens producing eggs for human consumption.

TURKEYS

Control of hexamitiasis caused by Hexamita meleagridis susceptible to oxytetracycline

100 g/ton

Feed continuously for 7-14 days

1

Control of infectious synovitis caused by Mycoplasma synoviae susceptible to oxytetracycline

200 g/ton

Feed continuously for 7-14 days

2

Control of complicating bacterial organisms associated with bluecomb (transmissible enteritis, coronaviral enteritis) susceptible to oxytetracycline

25 mg/lb of body weight daily

Feed continuously for 7-14 days

8.351

WARNING: At 200 g/ton use level or higher, withdraw 5 days before slaughter. Zero-day withdrawal period for lower use levels. Do not administer to turkeys producing eggs for human consumption.

SWINE

Treatment of bacterial enteritis caused by E. coli and Salmonella choleraesuis susceptible to oxytetracycline and treatment of bacterial pneumonia caused by Pasteurella multocida susceptible to oxytetracycline; treatment and control of colibacillosis (bacterial enteritis) caused by E. coli susceptible to neomycin

10 mg/lb of body weight daily

Feed continuously for 7-14 days

52

For breeding swine for control and treatment of Leptospirosis (reducing the incidence of abortion and shedding of leptospirae) caused by Leptospira pomona susceptible to oxytetracycline

10 mg/lb of body weight daily

Feed continuously for not more than 14 days

52

WARNING: 5-day withdrawal before slaughter at 10 mg/lb dosage.

CALVES, BEEF CATTLE, AND NONLACTATING DAIRY CATTLE

For growing cattle (over 400 lb) for reduction of liver condemnation due to liver abscesses

75 mg/head/day

Feed continuously

0.753

Prevention and treatment of the early stages of shipping fever complex

0.5-2.0 g/head/day

Feed 3-5 days before and after arrival in feedlots

5-203

Treatment of bacterial enteritis caused by E. coli and bacterial pneumonia (shipping fever complex) caused by Pasteurella multocida susceptible to oxytetracycline; treatment and control of colibacillosis (bacterial enteritis) caused by E. coli susceptible to neomycin

10 mg/lb of body weight daily

Feed continuously for 7-14 days

Treatment should continue 24 to 48 hours beyond remission of disease symptoms.

504

For calves (up to 250 lb) for treatment of bacterial enteritis caused by E. coli susceptible to oxytetracycline; treatment and control of colibacillosis (bacterial enteritis) caused by E. coli susceptible to neomycin

10 mg/lb of body weight daily

Feed continuously for 7-14 days

Treatment should continue 24 to 48 hours beyond remission of disease symptoms.

105

WARNING: A withdrawal period has not been established in preruminating calves; do not use in calves to be processed for veal. At the 0.5-2.0 g/head/day and 10 mg/lb levels: A milk discard time has not been established for use in lactating dairy cattle; do not use in female dairy cattle 20 months of age or older. At the 10 mg/lb level, withdraw 5 days before slaughter. Use of more than one product containing neomycin or failure to follow withdrawal times may result in illegal drug residues.

SHEEP

Treatment of bacterial enteritis caused by E. coli and bacterial pneumonia caused by Pasteurella multocida susceptible to oxytetracycline; treatment and control of colibacillosis (bacterial enteritis) caused by E. coli susceptible to neomycin

10 mg/lb of body weight daily

Feed continuously for 7-14 days

Treatment should continue 24 to 48 hours beyond remission of disease symptoms.

126

WARNING: 5-day withdrawal before slaughter at 10 mg/lb dosage.

1If bird weighs 10 lb, consuming 0.6 lb of complete feed per day

2If pig weighs 100 lb, consuming 4 lb of complete feed per day

3Include in feed supplement based on consumption of 2 lb of supplement per head per day

4If animal weighs 500 lb, consuming 2 lb of supplement per head per day

5If calf weighs 100 lb, consuming 2 lb of complete starter feed per day

6If lamb weighs 60 lb, consuming 1 lb of supplement per head per day

FOR USE IN ANIMAL FEEDS ONLY

NOT FOR HUMAN USE

RESTRICTED DRUG (CALIFORNIA) – USE ONLY AS DIRECTED

NEO-TERRAMYCIN is a registered trademark of Pfizer, Inc

licensed to Phibro Animal Health Corporation for Neomycin-Oxytetracycline

PHIBRO and PHIBRO logo design are trademarks owned by

Phibro Animal Health Corporation or its affiliates.

Phibro Animal Health Corporation, Teaneck, NJ 07666

SEE BACK PANEL FOR COMPLETE MIXING DIRECTIONS

USE DIRECTIONS AND WARNINGS

Net Weight 50 lb (22.7 kg)

Approved by FDA under NADA # 094-975

8851000

101-9069-07

Neo-Terramycin 100-100

NeoTerramycin 100-100

NEO-TERRAMYCIN 100/100 
neomycin-oxytetracycline powder
Product Information
Product TypeVFD TYPE A MEDICATED ARTICLE ANIMAL DRUGItem Code (Source)NDC:66104-8851
Route of AdministrationORAL
Active Ingredient/Active Moiety
Ingredient NameBasis of StrengthStrength
OXYTETRACYCLINE HYDROCHLORIDE (UNII: 4U7K4N52ZM) (OXYTETRACYCLINE ANHYDROUS - UNII:SLF0D9077S) OXYTETRACYCLINE HYDROCHLORIDE100 g  in 0.45 kg
NEOMYCIN SULFATE (UNII: 057Y626693) (NEOMYCIN - UNII:I16QD7X297) NEOMYCIN SULFATE100 g  in 0.45 kg
Inactive Ingredients
Ingredient NameStrength
MINERAL OIL (UNII: T5L8T28FGP)  
SODIUM ALUMINOSILICATE (UNII: 058TS43PSM)  
RICE BRAN (UNII: R60QEP13IC)  
Packaging
#Item CodePackage DescriptionMarketing Start DateMarketing End Date
1NDC:66104-8851-022.7 kg in 1 BAG
Marketing Information
Marketing CategoryApplication Number or Monograph CitationMarketing Start DateMarketing End Date
NADANADA09497503/24/2010
Labeler - Phibro Animal Health (006989008)
Registrant - Phibro Animal Health (006989008)
Establishment
NameAddressID/FEIBusiness Operations
Sichuan Long March Pharmaceutical Co. Ltd.544881741api manufacture

Revised: 8/2023
Document Id: 718eeffc-377e-4750-9415-1a53d3bf53bb
Set id: 3e2a3dc9-6ae2-4e0c-9e2a-e1cf042c6587
Version: 9
Effective Time: 20230802
 
Phibro Animal Health