Indications

Indications:  Ivermax (ivermectin) Pour-On applied at the recommended dose level of 500 mcg/kg is indicated for the effective treatment and control of these parasites.

Gastrointestinal Roundworms

Ostertagia ostertagi               (adults and L4)

    (including inhibited state)

Haemonchus placei                (adults and L4)

Trichostrongylus axei              (adults and L4)

T. colubriformis                      (adults and L4)

Cooperia oncophora                (adults and L4)

Cooperia punctata                  (adults and L4)

Cooperia surnabada                (adults and L4)

Strongyloides papillosus          (adults)

Oesophagostomum radiatum   (adults and L4)

Trichuris spp.                         (adults)

Lungworms

Dictyocaulus viviparus            (adults and L4)

Cattle Grubs                   (parasitic stages)

Hypoderma bovis

H. lineatum

Mites

Sarcoptes scabiei var. bovis

Lice

Linognathus vituli

Haematopinus eurysternus

Damalinia bovis

Solenopotes capillatus

Horn Flies

Haematobia irritans

Treatment of Cattle for Horn Flies:  Ivermax (ivermectin) Pour-On controls horn flies (Haematobia irritans) for up to 28 days after dosing.  For best results Ivermax (ivermectin) Pour-On should be part of a parasite control program for both internal and external parasites based on the epidemiology of these parasites.  Consult your veterinarian or an entomologist for the most effective timing of applications.

Persistent Activity:  Ivermax (ivermectin) Pour-On has been proven to effectively control infections and to protect cattle from re-infection with Ostertagia ostertagi, Oesophagostomum radiatum, Haemonchus placei, Trichostrongylus axei, Cooperia punctata and Cooperia oncophora for 14 days after treatment.

Dosage and Administration

Dosage:  The dose rate is 1 mL for each 22 lb of body weight.  The formulation should be applied along the topline in a narrow strip extending from the withers to the tailhead.

Administration:  Backpack (169 fl. oz/5 Liter Pack). 

Connect the applicator gun to the backpack as follows:  Attach the open end of the draw-off tubing to the dosing equipment.  (Because of the solvents used in the formulation, only the Protector Drench Gun from Instrument Supplies Limited, or equivalent, is recommended.  Other applicators may exhibit compatibility problems resulting in locking, incorrect dosage or leakage).

Replace the shipping cap with the draw-off cap.

Attach draw-off tubing to the draw-off cap.

Gently prime the applicator gun, checking for leaks.

Follow the manufacturer's directions for adjusting the dose.

When the interval between uses of the applicator gun is expected to exceed 12 hours, disconnect the gun and draw-off tubing from the product container and empty the product from the gun and tubing back into the product container.  To prevent removal of special lubricants from the Protector Drench Gun, the gun and tubing must not be washed.

Free Standing 676 fl. oz./20 Liter bottle

Connect the applicator gun to the 676 fl. oz./20 L bottle as follows:  Attach the open end of the draw-off tubing to the dosing equipment.  (Because of the solvents used in the formulation, only the Protector Drench Gun from Instrument Supply Limited, or equivalent is recommended.  Other applicators may exhibit compatibility problems resulting in locking, incorrect dosage or leakage.)

Replace the shipping cap with the draw-off cap and tighten down.

Attach draw-off tubing to the draw-off cap.

Gently prime the applicator gun, checking for leaks.

Follow the manufacturer's directions for adjusting the dose.

When the interval between uses of the applicator gun is expected to exceed 12 hours, disconnect the gun and draw-off tubing from the product container and empty the product from the gun and the tubing back into the product container.  To prevent removal of special lubricants from the Protector Drench Gun, the gun and tubing must not be washed.

Mode of Action

Mode of Action:  Ivermectin is a member of the macrocyclic lactone class of endectocides which have a unique mode of action.  Compounds of the class bind selectively and with high affinity to glutamate-gated chloride ion channels which occur in invertebrate nerve and muscle cells.  This leads to an increase in the permeability of the cell membrane to chloride ions with hyperpolarization of the nerve or muscle cell, resulting in paralysis and death of the parasite.  Compounds of this class may also interact with other ligand-gated chloride channels, such as those gated by the neurotransmitter gamma-aminobutyric acid (GABA).  The margin of safety for compounds of this class is attributable to the fact that mammals do not have the glutamate-gated chloride channel, the macrocyclic lactones have a low affinity for other mammalian ligand-gated chloride channel and they do not readily cross the blood-brain barrier.

Animal Safety

Animal Safety:  Studies conducted in the U.S.A. have demonstrated the safety margin for ivermectin.  Based on plasma levels, the topically applied formulation is expected to be at least as well tolerated by breeding animals as is the subcutaneous formulation which has no effect on breeding performance.

Residue Information

Residue Information:  Cattle must not be treated within 48 days of slaughter for human consumption.  Because a withdrawal time in milk has not been established, do not use in female dairy cattle of breeding age.  A withdrawal period has not been established for this product in pre-ruminating calves.  Do not use in calves to be processed for veal.

Warning

WARNING!  NOT FOR USE IN HUMANS.

This product should not be applied to self or others because it may be irritating to human skin and eyes and absorbed through the skin.  To minimize accidental skin contact, the user should wear a long-sleeved shirt and rubber gloves.  If accidental skin contact occurs, wash immediately with soap and water.  If accidental eye exposure occurs, flush eyes immediately with water and seek medical attention.

Keep this and all drugs out of the reach of children.

The Material Safety Data Sheet (MSDS) contains more detailed occupational safety information.  To report adverse effects, obtain an MSDS or for assistance contact Bimeda, Inc. at 1-888-524-6332.

WARNING!  FLAMMABLE!

KEEP AWAY FROM HEAT, SPARKS, OPEN FLAME, AND OTHER SOURCES OF IGNITION.

Precautions

PRECAUTIONS

Store away from excessive heat (104 degrees F/40 degrees C) and protect from light.

Use only in well-ventilated areas or outdoors.

Close container tightly when not in use.

Cattle should not be treated when hair or hide is wet since reduced efficacy may be experienced.

Do not use when rain is expected to wet cattle within six hours after treatment.

This product is for application to skin surface only.  Do not give orally or parenterally.

Package Label Display Panel

IVERMAX

(ivermectin) Pour-On for Cattle

Parasiticide

Kills:  Roundworms (including Brown Stomach Worm), Lungworms, Grubs, Sucking Lice, Biting Lice, Mange Mites, Horn Flies

NET CONTENTS:  676 fl oz (20 Liter)

Contains 800-550 lb Doses

WARNING!  FLAMMABLE!  KEEP AWAY FROM HEAT, SPARKS, OPEN FLAME AND OTHER SOURCES OF IGNITION.

WARNING!  NOT FOR USE IN HUMANS.

ANADA 200-318, Approved by FDA